Capturing the Perfect Reference Genome
نویسندگان
چکیده
منابع مشابه
Accelerating Haplotype-Based Genome-Wide Association Study Using Perfect Phylogeny and Phase-Known Reference Data
The genome-wide association study (GWAS) has become a routine approach for mapping disease risk loci with the advent of large-scale genotyping technologies. Multi-allelic haplotype markers can provide superior power compared with single-SNP markers in mapping disease loci. However, the application of haplotype-based analysis to GWAS is usually bottlenecked by prohibitive time cost for haplotype...
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RNA-sequencing is a new method of transcriptome characterization of organisms. Based on identity and relatedness, there are large genetic variations among different cattle breeds. The goal of the current study was to sequence the transcriptome of Guilan native cow and compare with available reference genome using RNA-sequencing method. Blood samples were collected from 14 Guilan native cows and...
متن کاملGenome Reference Consortium
NCBI is a member of the Genome Reference Consortium (GRC), an international collaboration that oversees updates and improvements to the human, mouse, and zebrafish reference genome assemblies. These reference assemblies include linear chromosome representations, unlocalized and unplaced scaffold sequences, and alternate loci scaffolds providing alternate sequence representations for genome regi...
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Modernizing Reference Genome Assemblies Deanna M. Church*, Valerie A. Schneider, Tina Graves, Katherine Auger, Fiona Cunningham, Nathan Bouk, Hsiu-Chuan Chen, Richa Agarwala, William M. McLaren, Graham R.S. Ritchie, Derek Albracht, Milinn Kremitzki, Susan Rock, Holland Kotkiewicz, Colin Kremitzki, Aye Wollam, Lee Trani, Lucinda Fulton, Robert Fulton, Lucy Matthews, Siobhan Whitehead, Will Chow,...
متن کاملReferenceNet: a semantic-pragmatic network for capturing reference relations
In this paper, we present ReferenceNet: a semantic-pragmatic network of reference relations between synsets. Synonyms are assumed to be exchangeable in similar contexts and also word embeddings are based on sharing of local contexts represented as vectors. Co-referring words, however, tend to occur in the same topical context but in different local contexts. In addition, they may express differ...
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ژورنال
عنوان ژورنال: BioTechniques
سال: 2010
ISSN: 0736-6205,1940-9818
DOI: 10.2144/000113484